The latest research on irritable bowel syndrome from China

The latest research on irritable bowel syndrome from China

Your Journey into Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a disorder characterized most commonly by cramping, abdominal pain, bloating, constipation, and diarrhea.

As its name indicates, Irritable Bowel Syndrome is a syndrome. That is, IBS is a combination of signs and symptoms, but not a disease. IBS is classified as a functional disorder. A functional disorder refers to a condition where the primary abnormality is an altered physiological function (the way the body works), rather than an identifiable inflammatory, infectious, structural, or biochemical cause.

Research also indicates that IBS is a multi-faceted disorder. For example, the symptoms of IBS result from what seems to be a disturbance or imbalance in the interaction between the intestines, the brain, sensory function, and the autonomic nervous system that alters regulation of bowel motility (motor function).

The articles on this site are provided to help you to better understand Irritable Bowel Syndrome and your options for relief of these symptoms.

Click Here For a Special Report on the causes and treatment of Irritable Bowel Syndrome

Author: Townsend Letter for Doctors and Patients

Keywords: Irritable bowel syndrome (IBS), Chinese medicine, Chinese herbal medicine, gastroenterology, constipation, diarrhea

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Irritable bowel syndrome is a common research topic for clinical trials in the People''s Republic of China, at least every other Chinese medical journal contains a report on a recent IBS RCT. Below are abstracts of some of the more recently published Chinese medical research on this common condition.

[ILLUSTRATION OMITTED]

Study 1: "The Treatment of 36 Cases of Constipation-type Irritable Bowel Syndrome with Shu Gan Li Qi Run Chang Tang (Course the Liver, Rectify the Qi & Moisten the Intestines Decoction)" by Wang Kui-ping, Zhe Jiang Zhong Yi Za Zhi (Zhejiang Journal of Chinese Medicine), #1, 2004, p. 19

Cohort description: Sixty-six patients with constipationtype IBS were enrolled in this study and randomly divided into two groups, a treatment group and a comparison group. In the treatment group, there were 36 patients, 15 males and 22 females aged 20-52 years, with an average age of 30.8 years. In the comparison group, there were 13 males and 17 females aged 18-50 years, with an average age of 28.6 years. All had suffered from constipation-type IBS for from eight months to six years, with an average disease duration of 2.8 years. Therefore, in terms of sex, age, and disease duration, these two groups were judged statistically comparable. All met the diagnostic criteria for constipation set forth in Zhong Yi Bing Zheng Zhen Duan Liao Xiao Biao Sun (Criteria for the Chinese Medical Diagnosis of Diseases and Patterns and Treatment Outcomes).

Treatment method: The members of the treatment group were administered the following self-composed Chinese medicinal formula: Radix Bupleuri (Chai Hu), Cortex Magnoliae Officinalis (Hou Po), and Radix Angelicae Sinensis (Dang Gui), 10g each, Fructus Citri Aurantii (Zhi Ke), Semen Arecae Catechu (Bin Lan), Semen Cannabis Sativae (Huo Ma Ren), and Semen Pruni (Yu Li Ren), 15g each, Radix Albus Paeoniae Lactiflorae (Bai Shao) and Tuber Curcumae (Yu Jin), 12g each, and mix-fried Radix Glycyrrhizae Uralensis (Gan Cao), 6g. If there was simultaneous intestine and stomach accumulation and heat, eight grams of uncooked Radix Et Rhizoma Rhei (Da Huang) were added. If there was simultaneous qi vacuity, 20 grams of Radix Astragali Membranacei (Huang Qi) and 15 grams of Radix Codonopsitis Pilosulae (Dang Shen) were added. If there was simultaneous yin vacuity intestinal dryness, 20 grams of uncooked Radix Rehmanniae Glutinosae (Sheng Di), 18 grams of Radix Scrophulariae Ningpoensis (Xuan Shen), and 10 grams of Tuber Ophiopogonis Japonici (Mai Men Dong) were added. If there was simultaneous yang vacuity, 20 grams of Herba Cistanchis Deserticoae Seu Salsae (Rou Cong Rong) and five grams of Lignum Aquilariae (Chen Xiang) were added. One packet of these medicinals was decocted in water and administered orally warm per day in two divided doses. Three weeks equaled one course of treatment.


05/02/2006
Levofloxacin-based Triple Therapy For Persistent Ulcer-Inducing Bacteria Successful
For those who suffer from stomach ulcers, the daily routine of breakfast, lunch and dinner can be painful. A common cause of these ulcers, as well as other gastric malignancies, is a bacterium called Helicobacter pylori. For some, this infection can be persistent and difficult to treat. Many approaches have been taken in an attempt to clear such infections, but with limited or unsuccessful outcomes. [click link for full article]

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04/26/2006
Gut Problems Caused By Long Term Stress Eased By Probiotics
Probiotics may help to reduce gut symptoms caused by long term stress, indicates research published ahead of print in the journal Gut.The researchers base their findings on analysis of gut tissue taken from rats subjected to either water avoidance stress, which involves placing the rat on a small platform surrounded by water, or sham stress for one hour a day for 10 consecutive days. [click link for full article]

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04/07/2006
Konsyl® Original Provides More Fiber Per Dose Than Traditional Bulk Forming Laxatives
Konsyl Pharmaceuticals, Inc., a leading producer of high quality, all natural fiber supplements for improving digestive health, offers Konsyl® Original as a powder-form, natural fiber supplement and bowel normalizer. Providing more fiber per dose than traditional bulk forming laxatives, Konsyl Original includes 6.0 grams of primarily soluble 100% psyllium fiber per dose. [click link for full article]

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03/03/2006
Data From Novogen Inflammatory Bowel Disease Drug Phase I Clinical Trial Shows Promise
A recentlycompleted Phase 1 clinical trial of an investigational drug to treatinflammatory bowel disease has demonstrated rapid absorption indicatingpotential for development as an oral therapy. The drug, NV-52, is an anti-inflammatory compound developed by Australianpharmaceutical company, Novogen Limited (Nasdaq: NVGN) (Australia: NRT). [click link for full article]

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02/13/2006
Gut Protein Found To Protect Against Infection And Intestinal Breakdown
A protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstructive jaundice or irritable bowel syndrome, researchers at UT Southwestern Medical Center have discovered."What we''ve identified is one of the mechanisms for how the body keeps the number of bacteria low in the small intestine, and how it prevents them from getting into other organs," said Dr. [click link for full article]

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